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Twins are scary, horror found that out long ago, there’s something about identical looking people that is inherently unsettling. Evil twins and dark halfs are what a large part of the genre is made of... at least I guess you never are Alone, with one of those.
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This image for The Descent is the kind of scene that always makes me want to look the other way, I guess anybody who ever lost a fingernail can easily understand why it is among the images that make me invariably whince*. 'Tis also probably why it is so popular use within the genre.

Wheelchairs, and the associated idea of disability scared me already as a kid, obviously one can’t out grow all of his fears.
To Sir with love, even the title has something unsettling.

Even running danger of coming off as a wimp, I still have to say that this poster artwork, for the French movie Frontiers, terrifies me.
The everyday news reality of it is much too close for my personal comfort.
I know that the idea of horror is to scare us, but must it be done in such a frightening way?

The idea of getting your tongue cut out or mouth sewn shut is a truly scary one when you think about it, to loose an important part of our ability to communicate with others that's truly a Art of the Devil.
*Another such scene is the fall/jump from heights. I have a practically pathological fear of breaking my leg.